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Issue Info: 
  • Year: 

    2025
  • Volume: 

    10
  • Issue: 

    1 (34)
  • Pages: 

    5-10
Measures: 
  • Citations: 

    0
  • Views: 

    26
  • Downloads: 

    0
Abstract: 

Introduction: The majority of embryo transfers (ETs) to date have been performed on day 3 to reduce the potential risk of fetal growth arrest. Transfer on day 5 provides higher clinical pregnancy outcomes with reduced risks of multiple pregnancies. This study aimed to evaluate the pregnancy outcome between day 5 embryo transfer and day 4 fresh embryo transfer in patients undergoing intracytoplasmic sperm injection (ICSI). Materials and Methods: This study was conducted at the Infertility Research Center of Sarem Hospital, Tehran, in 1402 on 921 infertile women who had been referred for ICSI. These patients were assigned to receive fresh embryo transfer (n=163) and blastocyst stage transfer (n=758). Statistical analyses were performed using SPSS software. Conclusion: There was no significant difference between the two groups in terms of mean age and pregnancy rate. The pregnancy rate on the fourth day (31.29%) was similar to that on the fifth day (28.50%) (PV <50.0). However, there was a significant difference between the two groups in terms of embryo quality (PV<0.05).

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2001
  • Volume: 

    59
  • Issue: 

    1
  • Pages: 

    26-28
Measures: 
  • Citations: 

    0
  • Views: 

    1954
  • Downloads: 

    0
Abstract: 

Breast cancer is a major cause of mortality in women due to malignant diseases and is the most prevalent type of cancer in western countries. According to investigations which has been done in Iran so far, the prevalence of disease in our country is also very high, therefore complete attention to clinical and pathological findings of this disease would be extremely essential. In this study, the direct relationship between axillary lymph node involvement and the aggressiveness of invasive ductal carcinoma has been brought into consideration.This study is a case series of 90 patients which all of them have had radical mastectomy because of breast cancer and all their samples has been referred to the center of pathology of Imam hospital. Based on modified Bloom-Richardson Grading, all the samples have been graded. The study of all lymph node samples related to above cases has also been conducted along with the main study.The most frequent ages of disease was 31 to 40 and left breast had most involvement. from all cases, 12.2% were in grade I with 27.2% lymph node involvement, 66.7% grade II with 73.4% lymph node involvement and 21.1% in grade III with 100% lymph node involvement (p=0.00008).Based on statistical analysis we concluded that the axillary lymph node involvement in brest cancer is strongly associated with the aggressiveness of invasive ductal carcinoma.This important point should not be neglected in planning for treatment of this kind of disease.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2012
  • Volume: 

    7
  • Issue: 

    1
  • Pages: 

    81-88
Measures: 
  • Citations: 

    0
  • Views: 

    1083
  • Downloads: 

    0
Abstract: 

Background: Personal values in each organization are the most effective factor in building a culture based of ethics. Nursing is a profession that needs ethical knowledge for guiding behaviors. So this research Grading the nurses personal values in Isfahan hospitals and match them with Islamic values.Methods: A categorical sample of 103 participants was selected. Rokeach Value Survey was used to measure values. The data were analyzed by spss-18.Results: the findings indicated that the most important terminal values were family security, wellbeing and salvation and the most instrumental values were honesty, capability and ambitious.Conclusion: By Identifying the values organizations would perceive the nature of ethics in individual levels.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2008
  • Volume: 

    32
  • Issue: 

    1 (64)
  • Pages: 

    31-36
Measures: 
  • Citations: 

    0
  • Views: 

    691
  • Downloads: 

    0
Abstract: 

Introduction: Mucoepidermoid carcinoma is the most common malignancy in salivary glands. This tumor has a variable biologic potential, so it was first divided into two groups: one with malignant behavior and the other with benign behavior and good prognosis. The purpose of this study was evaluation of TP53 oncoprotein and its relation to different grades of mucoepidermoid carcinoma. Materials & Methods: This retrospective study included 22 paraffin embedded mucoepidermoid carcinoma samples stained by H&E. The samples were classified into low grade, intermediate grade and high grade. Then, new sections were made and stained by immunohistochemistry method (IHC method) for TP53 marker. Finally, the relation between the two methods was statistically (ANOVA and Kendall test) analyzed. Seven sections of normal salivary gland tissue were also used as control group. Results: All control cases were negative for TP53 marker while 68.2% of mucoepidermoid carcinoma samples were positive. A significant relation was revealed between histological grade and nuclear TP53 staining by IHC method.Conclusion: Parallel to increasing histologic grade of salivary gland mucoepidermoid carcinoma, TP53 expression is also increased so that immunohistochemistry technique is helpful for determination of the biologic behavior of salivary gland mucoepidermoid corcinoma and prognosis of patients.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    1390
  • Volume: 

    0
Measures: 
  • Views: 

    383
  • Downloads: 

    0
Abstract: 

مقدمه: سلولهای بنیادی یکی از بهترین منابع برای تولید بافت بشمار می روند و انتقال ژن به این سلولها روش مناسبی برای تولید بافت و انتقال پروتئین هاست. از سوی دیگر سلول های بنیادی به دلیل قابلیت خودنوزایی، جداسازی نسبتا آسان آنها و توانایی مهاجرت به سمت بافتهای دچار کمبود اکسیژن، به عنوان روش درمان مناسب برای رگ زایی بکار میروند. مهمترین مساله در بکارگیری این سلولها یافتن روشی مناسب برای انتقال ژن است. حاملین غیرویروسی طراحی شده بر اساس پلیمرهای کاتیونی کارایی بالایی در این زمینه دارند و همچنین مشکلات ایمنی استفاده از حامل های ویروسی را ندارد. در این مطالعه تولید سلولهای بنیادی با بیان بالایVEGF بوسیله نانوذرات زیست تخریب پذیر پلیمر-DNA بررسی میشود.Roly (b-amino esters) دسته ای از پلیمرهای زیست تخریب پذیر هستند که قادرند از طریق تشکیل پیوندهای الکتروستاتیک با DNA در آب یا بافر در pHفیزیولوژیک میانکنش داده و نانوذراتی را تشکیل دهند که برای انتقال ژن مناسبند. در سلول های تیمار شده افزایش تولید hVEGF، قابلیت زیستی و پیوند شدن به بافت هدف مشاهده شد.روش ها: Roly (b-amino esters) سنتز شد. سه پلیمر با انتهای تغییر یافته (C32-117، C32-103 و C32-122) که کارایی بالایی در ترانسفیکاسیون سلول های بنیادی داشتند انتخاب شدند. سلول های مزانشیمی مشتق از مغز استخوان(hMSCs) و سلول های مشتق از جنین انسان(hESdCs) با وکتور حامل VEGF و یا پلاسمید کنترل (EGFP or luciferase) در شرایط بهینه ترانسفیکسیون با Roly (b-amino esters) آلوده شدند. تمام constructها (1.0´106 سلول در هر داربست) در فضای s.c. ناحیه پشتی موشهای فاقد تیموس(athymic) ایمپلنت شدند. تولید VEGF در سلول های بنیادی آلوده شده بررسی شد.RNA تام سلولی استخراج و cDNA سنتز شد. Quantitative PCRانجام داده شد و تمایز اندوتلیال با بررسی بیان سه ژن PECAM، Tie2 و vWF و میزان رگ زایی در فضای s.c. 2 یا 3 هفته پس از پیوند شدن مطالعه شد.یافته ها: پس از 2 هفته کشت در محیط رشد اندوتلیال، تمام سلولهای ترانسفکت شده با نانوذرات حامل VEGF سطح بیان بالاتری از مارکرهای اندوتلیال را نسبت به گروه کنترل تیمار نشده داشتند. در مقایسه با داربست کنترل بدون سلول، مهاجرت رگهای خونی از درون داربست های پوشیده شده با سلول های مزانشیمی آلوده شده با VEGF به کمک سه پلیمر Roly (b-amino esters) به بافتهای اطراف افزایش یافته بود. 4 روز پس از ترانسفیکاسیون، ترشح VEGF از سلول های مزانشیمی آلوده شده با VEGF و سلول های مشتق از جنین تقریبا 1 تا 3 برابر بیشتر از گروه کنترل آلوده نشده و 1 تا 2 برابر بیشتر از سلول های آلوده شده به Lipofectamine 2000 بود.بحث و نتیجه گیری: در این مطالعه نشان داده شد که مشتقات Roly (b-amino esters) با انتهای تغییر یافته حاملین غیر ویروسی مناسبی جهت انتقال ژن به Embryonic-derived stem cells هستند.

Yearly Impact:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

DEB S.S. | MARISETTY V.B.

Issue Info: 
  • Year: 

    2010
  • Volume: 

    34
  • Issue: 

    9
  • Pages: 

    2294-2305
Measures: 
  • Citations: 

    1
  • Views: 

    140
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

Issue Info: 
  • Year: 

    2017
  • Volume: 

    13
  • Issue: 

    1
  • Pages: 

    0-0
Measures: 
  • Citations: 

    1
  • Views: 

    79
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

MCLAUGHLIN G. HARRY

Journal: 

JOURNAL OF READING

Issue Info: 
  • Year: 

    1969
  • Volume: 

    12
  • Issue: 

    8
  • Pages: 

    639-646
Measures: 
  • Citations: 

    1
  • Views: 

    131
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Author(s): 

SIMONE VALLEBUENA D.

Journal: 

ANNALS ENDOCRINOLOGY

Issue Info: 
  • Year: 

    1999
  • Volume: 

    60
  • Issue: 

    -
  • Pages: 

    134-136
Measures: 
  • Citations: 

    1
  • Views: 

    85
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Issue Info: 
  • Year: 

    2023
  • Volume: 

    10
  • Issue: 

    2
  • Pages: 

    112-119
Measures: 
  • Citations: 

    0
  • Views: 

    32
  • Downloads: 

    11
Abstract: 

Purpose: Fatty liver is the most common chronic liver disease, and finding the appropriate method for detecting the problem is necessary. The current study aimed to quantity liver steatosis using Computed Tomography (CT), ultrasound images, and Alanine Aminotransferase (ALT) blood test. Materials and Methods: In this work, 163 Non-Alcoholic Fatty Liver Disease (NAFLD) patients implemented CT and ultrasound images on their abdomen regions. The liver and spleen density were calculated using CT images (as the standard method), and then the patients were divided into mild, and moderate to severe groups. During the sonography, an M-value histogram of the liver and the right kidney was drawn and their ratio (liver/kidney) was considered as a Hepatorenal Index (HRI). Mann-Whitney test was used to evaluate the relationships between HRI and ALT values. Results: The mean and standard deviation of the liver density in CT scans were obtained as 51 ±,4 HU. The HRI had better performance (Area Under the Curve, AUC: 0. 94) than the ALT (AUC: 0. 88) in determining liver steatosis. In addition, there was a significant difference between the mild, and moderate to severe groups (P < 0. 001) in HRI and ALT values. Conclusion: Based on the results, HRI is an excellent factor to distinguish between mild, and moderate to severe fatty liver. Notably, HRI is reproducible and operator-independent.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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